Clinical Pipeline

Nexavar (sorafenib) tablets

Liver Cancer

Locoregional therapy with TACE SPACE

Adjuvant STORM

Nexavar w/ Tarceva® SEARCH

Kidney Cancer

Advanced Kidney Cancer

Adjuvant SORCE/ASSURE

Non-Small Cell Lung Cancer

Third/Fourth-line, monotherapy

Thyroid Cancer

Monotherapy

Breast Cancer

Capecitabine +/-

First/second-line, gemcitabine or capecitabine +/-

First-line, docetaxel or letrozole +/-

Ovarian Cancer

Maintenance

Colorectal Cancer

Combination

Multiple Myeloma

Relapsed, lenalidomide/dexamethasone ASPIRE

Relapsed/refractory, monotherapy FOCUS

Solid Tumor

Monotherapy

Cell Cycle Kinase Inhibitor

ONX 0801 (TS Inhibitor)

ONX 0803* (JAK inhibitor)

ONX 0805* (JAK inhibitor)

ONX 0912 (oral proteasome inhibitor)

ONX 0914 (immunoproteasome inhibitor)

* subject to option exercise